MyBioSource.com's MCM6 Antibody (N-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot. The MCM6 Antibody (N-term) was generated using MCM6, and P105MCM as the antigen and it reacts with Human.
Description
The protein encoded by this gene is one of the highly
conserved mini-chromosome maintenance proteins (MCM) that are
essential for the initiation of eukaryotic genome replication. The
hexameric protein complex formed by the MCM proteins is a key
component of the pre-replication complex (pre_RC) and may be
involved in the formation of replication forks and in the
recruitment of other DNA replication related proteins. The MCM
complex consisting of this protein and MCM2, 4 and 7 proteins
possesses DNA helicase activity, and may act as a DNA unwinding
enzyme. The phosphorylation of the complex by CDC2 kinase reduces
the helicase activity, suggesting a role in the regulation of DNA
replication